Primary side effect

Secondary side effect

Author

n patients (Pat.)

Erythema

Ecchymosis

Hematoma

Edema

Pruritus

Pain

Papule

Nodule

Granuloma

Hyperpigmentation, Depigmentation

Fabi, Goldman 2012 [20]

n = 90

10%

17%

19%

7%

Narins et al. 2010 [21]

n = 116

2.6%

0.9%

5.2%

8.6%

6.9%

Vleggar 2006 [14]

Not specified

11%

1.2%

3.2%

0.14%

Palm et al. 2010 [22]

n = 130

41%

23%

8.5%

0.7%

Lowe et al. 2009 [23]

n = 221

39%

23%

20%

Schierle, Casas 2011 [24]

n = 106

4.7%

Zielke et al. 2008 [28]

n = 13

5.9%

9.8%

25%

9.8%

66.7%

17%

Woerle 2004 [16]

n = 300

10%* 1%**